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Quick Answer
A 1st quartile CASPer result means your applicant quartile was in the lowest quartile of your comparison group for that test type. In plain English, other applicants in the same test type and cohort generally had stronger responses.
That matters, but it does not mean you failed CASPer. It also does not tell you exactly how every program will use the result. CASPer is one component in an admissions file, and programs may weigh it differently alongside grades, experiences, essays, references, interviews, and other application materials.